Key issues in non-viral gene delivery

Key issues in non-viral gene delivery

Source :

• Advanced Drug Delivery Reviews [ 0169-409X ] ; 2001.

English descriptors

• Teeft :
  • Acad, Adult mouse, Aerosol delivery, Airway, Airway epithelia, Alveolar macrophages, Amphipathic helices, Apical surface, Biodistribution, Biodistribution routes, Biol, Biological barriers, Blood circulation, Blood components, Blood pressure, Brosis, Cancer gene therapy, Capillary permeability, Cationic, Cationic component, Cationic gene delivery, Cationic gene transfer, Cationic lipid, Cationic lipids, Cationic lipoplexes, Cationic liposome, Cationic particles, Cationic polymer, Cationic polymers, Cell culture systems, Cell transfection, Cellular interactions, Cftr gene transfer, Charge ratio, Chem, Chloroquine, Clinical indication, Condensed particles, Considerable interest, Critical issue, Cystic, Degradative pathway, Deliv, Delivery, Delivery systems, Direct gene transfer, Direct injection, Drug carrier syst, Drug deliv, Drug delivery, Drug delivery reviews, Drug delivery scientists, Elsevier science, Endosomal, Endosomal compartment, Endosome, Endothelium, Epithelium, Eukaryotic cells, Gene, Gene delivery, Gene delivery systems, Gene expression, Gene expression systems, Gene medicine, Gene products, Gene therapy, Gene transfer, Hashida, High concentrations, High levels, Higher levels, Hydrophilic polymers, Injection, Injection site, Intracellular, Intramuscular injection, Intravenous, Intravenous administration, Intravenous injection, Kupffer cells, Lipid, Lipid membranes, Lipoplexes, Liposome, Liposome complexes, Local effect, Local injection, Lung biology, Lung endothelia, Lung epithelia, Lung epithelium, Lung surfactant, Lymphatic drainage, Lymphatic system, Macromolecule, Major determinant, Many cells, Marcel dekker, Molecular complexes, Molecular motors, Molecular weight, Mouse models, Mouse muscle, Nagase rats, Nasal epithelium, Natl, Nuclear envelope, Nuclear import, Nuclear membrane, Nuclear pore, Nucleic acids, Partial correction, Particle bombardment, Particulate systems, Passive process, Pharm, Pharmaceutical products, Pharmacokinetic considerations, Plasma clearance, Plasma membrane, Plasmid, Polyelectrolyte complexes, Polymer, Pouton, Proc, Proton sponge hypothesis, Receptor, Reporter gene, Scavenger receptors, Seymour, Simian virus, Sodium glycocholate, Solid tissues, Solid tumours, Starburst dendrimers, Systemic circulation, Systemic delivery, Takakura, Target cells, Target site, Transfecting activity, Transfection, Trends cell biol, Tumour, Tumour tissue, Uptake, Vesicle, Vesicular stage, Viruslike particles, Vivo, Vivo transfection, Xenopus oocytes.

Abstract

• https://api.istex.fr/ark:/67375/6H6-BMB34MH8-L/fulltext.pdf

Affiliations:

• Royaume-Uni
• Angleterre, Midlands de l'Ouest
• Birmingham
• Université de Birmingham

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